What is Tabex?

Tabex® is a plant-based smoking cessation aid developed in Bulgaria. It contains cytisine – a natural alkaloid extracted from Laburnum anagyroides (Golden Rain). Cytisine acts as a nicotine receptor partial agonist, mimicking nicotine’s effects to reduce withdrawal symptoms and help users quit smoking naturally.

History and Scientific Background

Cytisine was first isolated in the 19th century, but its medical application was developed by Bulgarian scientists in the 1950s. Tabex® was first produced in 1964 following the work of Prof. Isaev, Prof. Paskov, and Dr. Dobrev. Key findings included:

• Lower toxicity than nicotine
• Less impact on the cardiovascular system
• High affinity to nicotine receptors

Tabex® has undergone clinical trials in Bulgaria, Germany, and Poland, demonstrating its safety and effectiveness.

How Does Tabex Work?

Cytisine binds to the same brain receptors as nicotine, easing cravings and withdrawal symptoms. It also prevents nicotine from binding, which helps reduce the satisfaction of smoking. The result is a decrease in physical dependence and an easier transition to a smoke-free life.

Additional benefits include mood stabilization and mild antidepressant effects due to stimulation of dopamine and noradrenaline release.

Treatment Schedule

The recommended Tabex® treatment lasts 25 days with a gradual reduction in dosage:

• Days 1–3: 1 tablet every 2 hours (6 tablets/day)
• Days 4–12: 1 tablet every 2.5 hours (5 tablets/day)
• Days 13–16: 1 tablet every 3 hours (4 tablets/day)
• Days 17–20: 1 tablet every 5 hours (3 tablets/day)
• Days 21–25: 1–2 tablets daily

Smoking should stop by day 5. If necessary, the treatment may be repeated after 2–3 months.

Clinical Studies and Safety

• Quit rates up to 55% after a complete 25-day course
• Effective in smokers with conditions like bronchitis, hypertension, and depression
• Well-tolerated, with no addictive properties
• Demonstrates mild antidepressant effects

Key Benefits of Tabex

• 100% natural active ingredient – cytisine
• Nicotine-free – not a nicotine replacement therapy
• Affordable and clinically proven
• Developed by Bulgarian scientists with over 60 years of research
• Widely used in Europe and recommended by doctors and pharmacists